Change scores were calculated for both primary outcomes (fatigue and physical functioning) by subtracting 20 and 70 week scores from baseline scores from). First, we examined simple descriptive statistics, by therapist and therapy type (PR vs SL) for both outcomes and measures of the therapeutic alliance. Since (as a result of the trial design) the controls are common to all six therapist by therapy type combinations, differences in the efficacy of these six combinations can be compared without reference to the controls. For example, the effect of pragmatic rehabilitation when delivered by therapist 1 is the difference in average outcome for PR delivered by therapist 1 and the average outcome in the controls. The effect of pragmatic rehabilitation when delivered by therapist 2 is the difference in average outcome for PR delivered by therapist 2 and the average outcome in the controls. Hence the difference in efficacy between these two therapists at delivering PR is simply the differen